In silico (computed) modelling of doses and dosing regimens associated with morphine levels above international legal driving limits

BACKGROUND: Morphine can cause central nervous system side effects which impair driving skills. The legal blood morphine concentration limit for driving is 20 µg/L in France/Poland/Netherlands and 80 µg/L in England/Wales. There is no guidance as to the morphine dose leading to this concentration. A...

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Detalles Bibliográficos
Autores principales: Boland, Jason W, Johnson, Miriam, Ferreira, Diana, Berry, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041735/
https://www.ncbi.nlm.nih.gov/pubmed/29724154
http://dx.doi.org/10.1177/0269216318773956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041735/
https://www.ncbi.nlm.nih.gov/pubmed/29724154
http://dx.doi.org/10.1177/0269216318773956

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