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In silico (computed) modelling of doses and dosing regimens associated with morphine levels above international legal driving limits
BACKGROUND: Morphine can cause central nervous system side effects which impair driving skills. The legal blood morphine concentration limit for driving is 20 µg/L in France/Poland/Netherlands and 80 µg/L in England/Wales. There is no guidance as to the morphine dose leading to this concentration. A...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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SAGE Publications
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041735/ https://www.ncbi.nlm.nih.gov/pubmed/29724154 http://dx.doi.org/10.1177/0269216318773956 |