Effects of an ActRIIB.Fc Ligand Trap on Cardiac Function in Simian Immunodeficiency Virus-Infected Male Rhesus Macaques

An important safety consideration in the use of antagonists of myostatin and activins is whether these drugs induce myocardial hypertrophy and impair cardiac function. The current study evaluated the effects of a soluble ActRIIB receptor Fc fusion protein (ActRIIB.Fc), a ligand trap for TGF-β/activi...

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Detalles Bibliográficos
Autores principales: Guo, Wen, Pencina, Karol M, Gagliano-Jucá, Thiago, Jasuja, Ravi, Morris, Nancy, O’Connell, Karyn E, Westmoreland, Susan, Bhasin, Shalender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041778/
https://www.ncbi.nlm.nih.gov/pubmed/30019021
http://dx.doi.org/10.1210/js.2018-00099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041778/
https://www.ncbi.nlm.nih.gov/pubmed/30019021
http://dx.doi.org/10.1210/js.2018-00099

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