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Roles of Gag-RNA interactions in HIV-1 virus assembly deciphered by single-molecule localization microscopy

During HIV-1 assembly, the retroviral structural protein Gag forms an immature capsid, containing thousands of Gag molecules, at the plasma membrane (PM). Interactions between Gag nucleocapsid (NC) and viral RNA (vRNA) are thought to drive assembly, but the exact roles of these interactions have rem...

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Detalles Bibliográficos
Autores principales: Yang, Yantao, Qu, Na, Tan, Jie, Rushdi, Muaz N., Krueger, Christopher J., Chen, Antony K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042153/
https://www.ncbi.nlm.nih.gov/pubmed/29891653
http://dx.doi.org/10.1073/pnas.1805728115