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Novel metrics for quantifying bacterial genome composition skews

BACKGROUND: Bacterial genomes have characteristic compositional skews, which are differences in nucleotide frequency between the leading and lagging DNA strands across a segment of a genome. It is thought that these strand asymmetries arise as a result of mutational biases and selective constraints,...

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Detalles Bibliográficos
Autores principales: Joesch-Cohen, Lena M., Robinson, Max, Jabbari, Neda, Lausted, Christopher G., Glusman, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042203/
https://www.ncbi.nlm.nih.gov/pubmed/29996771
http://dx.doi.org/10.1186/s12864-018-4913-5