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LAMP3 plays an oncogenic role in osteosarcoma cells partially by inhibiting TP53

BACKGROUND: Osteosarcoma (OS) is a common malignant tumor that predominantly occurs in adolescents. Its most common metastasis is to the lungs. As shown in our earlier study, lysosome-associated membrane glycoprotein 3 (LAMP3) is highly upregulated in metastatic OS. However, its role in the regulati...

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Detalles Bibliográficos
Autores principales: Liu, Shaoxian, Yue, Junyi, Du, Wei, Han, Jian, Zhang, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042264/
https://www.ncbi.nlm.nih.gov/pubmed/30008754
http://dx.doi.org/10.1186/s11658-018-0099-8