Sustained high glucose exposure sensitizes macrophage responses to cytokine stimuli but reduces their phagocytic activity

BACKGROUND: Macrophages are tissue resident immune cells important for host defence and homeostasis. During diabetes, macrophages and other innate immune cells are known to have a pro-inflammatory phenotype, which is believed to contribute to the pathogenesis of various diabetic complications. Howev...

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Detalles Bibliográficos
Autores principales: Pavlou, Sofia, Lindsay, Jaime, Ingram, Rebecca, Xu, Heping, Chen, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042333/
https://www.ncbi.nlm.nih.gov/pubmed/29996768
http://dx.doi.org/10.1186/s12865-018-0261-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042333/
https://www.ncbi.nlm.nih.gov/pubmed/29996768
http://dx.doi.org/10.1186/s12865-018-0261-0

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