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Sustained high glucose exposure sensitizes macrophage responses to cytokine stimuli but reduces their phagocytic activity
BACKGROUND: Macrophages are tissue resident immune cells important for host defence and homeostasis. During diabetes, macrophages and other innate immune cells are known to have a pro-inflammatory phenotype, which is believed to contribute to the pathogenesis of various diabetic complications. Howev...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042333/ https://www.ncbi.nlm.nih.gov/pubmed/29996768 http://dx.doi.org/10.1186/s12865-018-0261-0 |