Long noncoding RNA PVT1 modulates hepatocellular carcinoma cell proliferation and apoptosis by recruiting EZH2

BACKGROUND: We aimed to figure out the molecular network of PVT1 and EZH2 on hepatocellular carcinoma (HCC) cells growth. We also explored the interaction between PVT1, EZH2, MDM2 and P53. METHODS: Microarray analysis was performed to screen for abnormally expressed genes in HCC tissues and PVT1 was...

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Detalles Bibliográficos
Autores principales: Guo, Jianping, Hao, Chong, Wang, Congcong, Li, Luo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042336/
https://www.ncbi.nlm.nih.gov/pubmed/30008615
http://dx.doi.org/10.1186/s12935-018-0582-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042336/
https://www.ncbi.nlm.nih.gov/pubmed/30008615
http://dx.doi.org/10.1186/s12935-018-0582-3

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