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Rational design of a quantitative, pH-insensitive, nucleic acid based fluorescent chloride reporter

Chloride plays a major role in cellular homeostasis by regulating the lumenal pH of intracellular organelles. We have described a pH-independent, fluorescent chloride reporter called Clensor that has successfully measured resting chloride in organelles of living cells. Here, we describe the rational...

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Detalles Bibliográficos
Autores principales: Prakash, Ved, Saha, Sonali, Chakraborty, Kasturi, Krishnan, Yamuna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042475/
https://www.ncbi.nlm.nih.gov/pubmed/30050672
http://dx.doi.org/10.1039/c5sc04002g