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Condensin II drives large-scale folding and spatial partitioning of interphase chromosomes in Drosophila nuclei

Metazoan chromosomes are folded into discrete sub-nuclear domains, referred to as chromosome territories (CTs). The molecular mechanisms that underlie the formation and maintenance of CTs during the cell cycle remain largely unknown. Here, we have developed high-resolution chromosome paints to inves...

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Detalles Bibliográficos
Autores principales: Rosin, Leah F., Nguyen, Son C., Joyce, Eric F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042687/
https://www.ncbi.nlm.nih.gov/pubmed/30001329
http://dx.doi.org/10.1371/journal.pgen.1007393