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Condensin II drives large-scale folding and spatial partitioning of interphase chromosomes in Drosophila nuclei
Metazoan chromosomes are folded into discrete sub-nuclear domains, referred to as chromosome territories (CTs). The molecular mechanisms that underlie the formation and maintenance of CTs during the cell cycle remain largely unknown. Here, we have developed high-resolution chromosome paints to inves...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042687/ https://www.ncbi.nlm.nih.gov/pubmed/30001329 http://dx.doi.org/10.1371/journal.pgen.1007393 |