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Deconvolution of expression microarray data reveals (131)I-induced responses otherwise undetected in thyroid tissue

High-throughput gene expression analysis is increasingly used in radiation research for discovery of damage-related or absorbed dose-dependent biomarkers. In tissue samples, cell type-specific responses can be masked in expression data due to mixed cell populations which can preclude biomarker disco...

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Detalles Bibliográficos
Autores principales: Langen, Britta, Rudqvist, Nils, Spetz, Johan, Helou, Khalil, Forssell-Aronsson, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042689/
https://www.ncbi.nlm.nih.gov/pubmed/30001320
http://dx.doi.org/10.1371/journal.pone.0197911