Ikaros cooperates with Notch activation and antagonizes TGFβ signaling to promote pDC development

Plasmacytoid and conventional dendritic cells (pDCs and cDCs) arise from monocyte and dendritic progenitors (MDPs) and common dendritic progenitors (CDPs) through gene expression changes that remain partially understood. Here we show that the Ikaros transcription factor is required for DC developmen...

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Detalles Bibliográficos
Autores principales: Mastio, Jérôme, Simand, Célestine, Cova, Giovanni, Kastner, Philippe, Chan, Susan, Kirstetter, Peggy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042690/
https://www.ncbi.nlm.nih.gov/pubmed/30001316
http://dx.doi.org/10.1371/journal.pgen.1007485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042690/
https://www.ncbi.nlm.nih.gov/pubmed/30001316
http://dx.doi.org/10.1371/journal.pgen.1007485

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