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In healthy volunteers, taking flucloxacillin with food does not compromise effective plasma concentrations in most circumstances

It is usually recommended that flucloxacillin is given on an empty stomach. The aim of this study was to compare total and free flucloxacillin concentrations after oral flucloxacillin, given with and without food, based on contemporary pharmacokinetic and pharmacodynamic targets. Flucloxacillin 1000...

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Detalles Bibliográficos
Autores principales: Gardiner, Sharon J., Drennan, Philip G., Begg, Ronald, Zhang, Mei, Green, Jared K., Isenman, Heather L., Everts, Richard J., Chambers, Stephen T., Begg, Evan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042703/
https://www.ncbi.nlm.nih.gov/pubmed/30001392
http://dx.doi.org/10.1371/journal.pone.0199370