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Downregulation of PIK3CA via antibody-esiRNA-complexes suppresses human xenograft tumor growth
Precision cancer therapy requires on the one hand detailed knowledge about a tumor’s driver oncogenes and on the other hand an effective targeted therapy that specifically inhibits these oncogenes. While the determination of genomic landscape of a tumor has reached a very precise level, the respecti...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042707/ https://www.ncbi.nlm.nih.gov/pubmed/30001368 http://dx.doi.org/10.1371/journal.pone.0200163 |