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A hierarchical Bayesian model to predict APOE4 genotype and the age of Alzheimer’s disease onset
In this work we use a hierarchical Bayesian paradigm to introduce a theoretical framework to determine an individual’s Apolipoprotein ε4 (APOE4) genotype, which heavily influences both the age of onset and probability of acquiring Alzheimer’s disease (AD). This calculation is based solely on an indi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042730/ https://www.ncbi.nlm.nih.gov/pubmed/30001420 http://dx.doi.org/10.1371/journal.pone.0200263 |