DDX3 suppresses type I interferons and favors viral replication during Arenavirus infection

Several arenaviruses cause hemorrhagic fever (HF) diseases that are associated with high morbidity and mortality in humans. Accordingly, HF arenaviruses have been listed as top-priority emerging diseases for which countermeasures are urgently needed. Because arenavirus nucleoprotein (NP) plays criti...

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Detalles Bibliográficos
Autores principales: Loureiro, María Eugenia, Zorzetto-Fernandes, Andre Luiz, Radoshitzky, Sheli, Chi, Xiaoli, Dallari, Simone, Marooki, Nuha, Lèger, Psylvia, Foscaldi, Sabrina, Harjono, Vince, Sharma, Sonia, Zid, Brian M., López, Nora, de la Torre, Juan Carlos, Bavari, Sina, Zúñiga, Elina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042795/
https://www.ncbi.nlm.nih.gov/pubmed/30001425
http://dx.doi.org/10.1371/journal.ppat.1007125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042795/
https://www.ncbi.nlm.nih.gov/pubmed/30001425
http://dx.doi.org/10.1371/journal.ppat.1007125

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