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Computation predicts rapidly adapting mechanotransduction currents cannot account for tactile encoding in Merkel cell-neurite complexes

Distinct firing properties among touch receptors are influenced by multiple, interworking anatomical structures. Our understanding of the functions and crosstalk of Merkel cells and their associated neurites—the end organs of slowly adapting type I (SAI) afferents—remains incomplete. Piezo2 mechanic...

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Detalles Bibliográficos
Autores principales: Gerling, Gregory J., Wan, Lingtian, Hoffman, Benjamin U., Wang, Yuxiang, Lumpkin, Ellen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042796/
https://www.ncbi.nlm.nih.gov/pubmed/29958280
http://dx.doi.org/10.1371/journal.pcbi.1006264