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A Novel Method to Detect Bias in Short Read NGS Data

Detecting sources of bias in transcriptomic data is essential to determine signals of Biological significance. We outline a novel method to detect sequence specific bias in short read Next Generation Sequencing data. This is based on determining intra-exon correlations between specific motifs. This...

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Detalles Bibliográficos
Autores principales: Alnasir, Jamie, Shanahan, Hugh P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042817/
https://www.ncbi.nlm.nih.gov/pubmed/28941355
http://dx.doi.org/10.1515/jib-2017-0025