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Computational Approaches to Identify Genetic Interactions for Cancer Therapeutics

The development of improved cancer therapies is frequently cited as an urgent unmet medical need. Here we describe how genetic interactions are being therapeutically exploited to identify novel targeted treatments for cancer. We discuss the current methodologies that use ‘omics data to identify gene...

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Detalles Bibliográficos
Autores principales: Benstead-Hume, Graeme, Wooller, Sarah K., Pearl, Frances M.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042820/
https://www.ncbi.nlm.nih.gov/pubmed/28941356
http://dx.doi.org/10.1515/jib-2017-0027