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Chronic and intermittent administration of systemic nitroglycerin in the rat induces an increase in the gene expression of CGRP in central areas: potential contribution to pain processing

BACKGROUND: Calcitonin gene related peptide (CGRP) is a key neuropeptide involved in the activation of the trigeminovascular system and it is likely related to migraine chronification. Here, we investigated the role of CGRP in an animal model that mimics the chronic migraine condition via repeated a...

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Detalles Bibliográficos
Autores principales: Greco, Rosaria, Demartini, Chiara, Zanaboni, Anna Maria, Tassorelli, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043463/
https://www.ncbi.nlm.nih.gov/pubmed/30003352
http://dx.doi.org/10.1186/s10194-018-0879-6