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Negligible contribution of M2634V substitution to ZIKV pathogenesis in AG6 mice revealed by a bacterial promoter activity reduced infectious clone
ZIKV has emerged as a significant human pathogene for the severe neurological complications, including Guillain-Barré(GBS) syndrome in adults and a variety of fetal abnormalities such as microcephaly. A stable and efficient infectious clone of Brazilian ZIKV isolate is required to study pathogenesis...
Autores principales: | Zhao, Fanfan, Xu, Yongfen, Lavillette, Dimitri, Zhong, Jin, Zou, Gang, Long, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043478/ https://www.ncbi.nlm.nih.gov/pubmed/30002446 http://dx.doi.org/10.1038/s41598-018-28890-0 |
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