Single-pot glycoprotein biosynthesis using a cell-free transcription-translation system enriched with glycosylation machinery

The emerging discipline of bacterial glycoengineering has made it possible to produce designer glycans and glycoconjugates for use as vaccines and therapeutics. Unfortunately, cell-based production of homogeneous glycoproteins remains a significant challenge due to cell viability constraints and the...

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Detalles Bibliográficos
Autores principales: Jaroentomeechai, Thapakorn, Stark, Jessica C., Natarajan, Aravind, Glasscock, Cameron J., Yates, Laura E., Hsu, Karen J., Mrksich, Milan, Jewett, Michael C., DeLisa, Matthew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043479/
https://www.ncbi.nlm.nih.gov/pubmed/30002445
http://dx.doi.org/10.1038/s41467-018-05110-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043479/
https://www.ncbi.nlm.nih.gov/pubmed/30002445
http://dx.doi.org/10.1038/s41467-018-05110-x

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