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Single-pot glycoprotein biosynthesis using a cell-free transcription-translation system enriched with glycosylation machinery
The emerging discipline of bacterial glycoengineering has made it possible to produce designer glycans and glycoconjugates for use as vaccines and therapeutics. Unfortunately, cell-based production of homogeneous glycoproteins remains a significant challenge due to cell viability constraints and the...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043479/ https://www.ncbi.nlm.nih.gov/pubmed/30002445 http://dx.doi.org/10.1038/s41467-018-05110-x |