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Exposure to Polycyclic Aromatic Hydrocarbons Leads to Non-monotonic Modulation of DNA and RNA (hydroxy)methylation in a Rat Model

Besides genetic modifications, rapidly growing evidence has linked environmental pollutants with epigenetic variations. To date, only a few studies have been performed on DNA methylation changes of polycyclic aromatic hydrocarbons (PAH), which showed contradictory results. These discrepancies might...

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Detalles Bibliográficos
Autores principales: Duca, Radu-Corneliu, Grova, Nathalie, Ghosh, Manosij, Do, Jean-Mikael, Hoet, Peter H. M., Vanoirbeek, Jeroen A. J., Appenzeller, Brice M. R., Godderis, Lode
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043565/
https://www.ncbi.nlm.nih.gov/pubmed/30002487
http://dx.doi.org/10.1038/s41598-018-28911-y