O-GlcNAcylation of FoxO1 mediates nucleoside diphosphate kinase B deficiency induced endothelial damage

Nucleoside diphosphate kinase B (NDPK-B) acts as a protective factor in the retinal vasculature. NDPK-B deficiency leads to retinal vasoregression mimicking diabetic retinopathy (DR). Angiopoetin 2 (Ang-2), an initiator of retinal vasoregression in DR, is upregulated in NDPK-B deficient retinas and...

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Detalles Bibliográficos
Autores principales: Shan, Shenliang, Chatterjee, Anupriya, Qiu, Yi, Hammes, Hans-Peter, Wieland, Thomas, Feng, Yuxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043576/
https://www.ncbi.nlm.nih.gov/pubmed/30002415
http://dx.doi.org/10.1038/s41598-018-28892-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043576/
https://www.ncbi.nlm.nih.gov/pubmed/30002415
http://dx.doi.org/10.1038/s41598-018-28892-y

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