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Rpn11-mediated ubiquitin processing in an ancestral archaeal ubiquitination system

While protein ubiquitination was long believed to be a truly eukaryotic feature, recently sequenced genomes revealed complete ubiquitin (Ub) modification operons in archaea. Here, we present the structural and mechanistic characterization of an archaeal Rpn11 deubiquitinase from Caldiarchaeum subter...

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Detalles Bibliográficos
Autores principales: Fuchs, Adrian C. D., Maldoner, Lorena, Wojtynek, Matthias, Hartmann, Marcus D., Martin, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043591/
https://www.ncbi.nlm.nih.gov/pubmed/30002364
http://dx.doi.org/10.1038/s41467-018-05198-1