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Autoantigen-Harboring Apoptotic Cells Hijack the Coinhibitory Pathway of T Cell Activation

Apoptosis is an important physiological process in development and disease. Apoptotic cells (ACs) are a major source of self-antigens, but ACs usually evade immune responses. The mechanism by which ACs repress T cell adaptive immune responses is poorly understood. T cell activation is finely regulat...

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Detalles Bibliográficos
Autores principales: Yakoub, Abraam M., Schulz, Ralph, Seiffert, Martina, Sadek, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043626/
https://www.ncbi.nlm.nih.gov/pubmed/30002409
http://dx.doi.org/10.1038/s41598-018-28901-0