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Autoantigen-Harboring Apoptotic Cells Hijack the Coinhibitory Pathway of T Cell Activation
Apoptosis is an important physiological process in development and disease. Apoptotic cells (ACs) are a major source of self-antigens, but ACs usually evade immune responses. The mechanism by which ACs repress T cell adaptive immune responses is poorly understood. T cell activation is finely regulat...
Autores principales: | Yakoub, Abraam M., Schulz, Ralph, Seiffert, Martina, Sadek, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043626/ https://www.ncbi.nlm.nih.gov/pubmed/30002409 http://dx.doi.org/10.1038/s41598-018-28901-0 |
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