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A Novel Stochastic Multi-Scale Model of Francisella tularensis Infection to Predict Risk of Infection in a Laboratory

We present a multi-scale model of the within-phagocyte, within-host and population-level infection dynamics of Francisella tularensis, which extends the mechanistic one proposed by Wood et al. (2014). Our multi-scale model incorporates key aspects of the interaction between host phagocytes and extra...

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Detalles Bibliográficos
Autores principales: Carruthers, Jonathan, López-García, Martín, Gillard, Joseph J., Laws, Thomas R., Lythe, Grant, Molina-París, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043654/
https://www.ncbi.nlm.nih.gov/pubmed/30034369
http://dx.doi.org/10.3389/fmicb.2018.01165