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Generation of dopamine neuronal-like cells from induced neural precursors derived from adult human cells by non-viral expression of lineage factors

Reprogramming technology holds great promise for the study and treatment of Parkinson’s disease (PD) as patient-specific ventral midbrain dopamine (vmDA) neurons can be generated. This should facilitate the investigation of early changes occurring during PD pathogenesis, permitting the identificatio...

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Detalles Bibliográficos
Autores principales: Playne, Rebecca, Jones, Kathryn, Connor, Bronwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Stem Cells and Regenerative Medicine 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043657/
https://www.ncbi.nlm.nih.gov/pubmed/30018471