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Leucine-Rich Glioma Inactivated 1 Promotes Oligodendrocyte Differentiation and Myelination via TSC-mTOR Signaling

Leucine-rich glioma inactivated 1 (Lgi1), a putative tumor suppressor, is tightly associated with autosomal dominant lateral temporal lobe epilepsy (ADLTE). It has been shown that Lgi1 regulates the myelination of Schwann cells in the peripheral nervous system (PNS). However, the function and underl...

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Detalles Bibliográficos
Autores principales: Xie, Ya-Jun, Zhou, Lin, Wang, Yin, Jiang, Nan-Wei, Cao, Shenglong, Shao, Chong-Yu, Wang, Xin-Tai, Li, Xiang-Yao, Shen, Ying, Zhou, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043672/
https://www.ncbi.nlm.nih.gov/pubmed/30034322
http://dx.doi.org/10.3389/fnmol.2018.00231