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GLP-1 receptor regulates cell growth through regulating IDE expression level in Aβ1–42-treated PC12 cells

This study aimed to validate whether glucagon-like peptide-1 receptor (GLP-1R) / cyclic adenosine monophosphate (cAMP) / protein kinase (PKA) / insulin-degrading enzyme (IDE) signaling pathway was associated with neuronal apoptosis. We developed an animal model presenting both Alzheimer’s disease (A...

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Detalles Bibliográficos
Autores principales: Li, Huajie, Cao, Liping, Ren, Yi, Jiang, Ying, Xie, Wei, Li, Dawen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043719/
https://www.ncbi.nlm.nih.gov/pubmed/29263141
http://dx.doi.org/10.1042/BSR20171284