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GLP-1 receptor regulates cell growth through regulating IDE expression level in Aβ1–42-treated PC12 cells
This study aimed to validate whether glucagon-like peptide-1 receptor (GLP-1R) / cyclic adenosine monophosphate (cAMP) / protein kinase (PKA) / insulin-degrading enzyme (IDE) signaling pathway was associated with neuronal apoptosis. We developed an animal model presenting both Alzheimer’s disease (A...
Autores principales: | Li, Huajie, Cao, Liping, Ren, Yi, Jiang, Ying, Xie, Wei, Li, Dawen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043719/ https://www.ncbi.nlm.nih.gov/pubmed/29263141 http://dx.doi.org/10.1042/BSR20171284 |
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