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Master Regulators Connectivity Map: A Transcription Factors-Centered Approach to Drug Repositioning

Drug discovery is a very expensive and time-consuming endeavor. Fortunately, recent omics technologies and Systems Biology approaches introduced interesting new tools to achieve this task, facilitating the repurposing of already known drugs to new therapeutic assignments using gene expression data a...

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Detalles Bibliográficos
Autores principales: De Bastiani, Marco A., Pfaffenseller, Bianca, Klamt, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043797/
https://www.ncbi.nlm.nih.gov/pubmed/30034338
http://dx.doi.org/10.3389/fphar.2018.00697