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Master Regulators Connectivity Map: A Transcription Factors-Centered Approach to Drug Repositioning
Drug discovery is a very expensive and time-consuming endeavor. Fortunately, recent omics technologies and Systems Biology approaches introduced interesting new tools to achieve this task, facilitating the repurposing of already known drugs to new therapeutic assignments using gene expression data a...
Autores principales: | De Bastiani, Marco A., Pfaffenseller, Bianca, Klamt, Fabio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043797/ https://www.ncbi.nlm.nih.gov/pubmed/30034338 http://dx.doi.org/10.3389/fphar.2018.00697 |
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