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Dimer‐specific immunoprecipitation of active caspase‐2 identifies TRAF proteins as novel activators

Caspase‐2 has been shown to initiate apoptotic cell death in response to specific intracellular stressors such as DNA damage. However, the molecular mechanisms immediately upstream of its activation are still poorly understood. We combined a caspase‐2 bimolecular fluorescence complementation (BiFC)...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Robeson, Alexander C, Lindblom, Kelly R, Wojton, Jeffrey, Kornbluth, Sally, Matsuura, Kenkyo
التنسيق: Online مقال نص
اللغة:English
منشور في: John Wiley and Sons Inc. 2018
الموضوعات:
الوصول للمادة أونلاين:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043850/
https://www.ncbi.nlm.nih.gov/pubmed/29875129
http://dx.doi.org/10.15252/embj.201797072