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Dimer‐specific immunoprecipitation of active caspase‐2 identifies TRAF proteins as novel activators

Caspase‐2 has been shown to initiate apoptotic cell death in response to specific intracellular stressors such as DNA damage. However, the molecular mechanisms immediately upstream of its activation are still poorly understood. We combined a caspase‐2 bimolecular fluorescence complementation (BiFC)...

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Detalles Bibliográficos
Autores principales: Robeson, Alexander C, Lindblom, Kelly R, Wojton, Jeffrey, Kornbluth, Sally, Matsuura, Kenkyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043850/
https://www.ncbi.nlm.nih.gov/pubmed/29875129
http://dx.doi.org/10.15252/embj.201797072

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