The novel estrogenic receptor GPR30 alleviates ischemic injury by inhibiting TLR4-mediated microglial inflammation

BACKGROUND: The steroid hormone estrogen (17-β-estradiol, E2) provides neuroprotection against cerebral ischemic injury by activating estrogen receptors. The novel estrogen receptor G protein-coupled receptor 30 (GPR30) is highly expressed in the brain and provides acute neuroprotection against stro...

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Detalles Bibliográficos
Autores principales: Zhang, Zengli, Qin, Pei, Deng, Youliang, Ma, Zhi, Guo, Hang, Guo, Haiyun, Hou, Yushu, Wang, Shiquan, Zou, Wangyuan, Sun, Yanyuan, Ma, Yulong, Hou, Wugang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043971/
https://www.ncbi.nlm.nih.gov/pubmed/30001721
http://dx.doi.org/10.1186/s12974-018-1246-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043971/
https://www.ncbi.nlm.nih.gov/pubmed/30001721
http://dx.doi.org/10.1186/s12974-018-1246-x

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