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Caveolin-1 is dispensable for early lymphoid development, but plays a role in the maintenance of the mature splenic microenvironment

OBJECTIVE: Caveolin-1 (CAV1) is known for its role as both a tumor suppressor and an oncogene, harboring a highly context-dependent role within a myriad of malignancies and cell types. In an immunological context, dysregulation of CAV1 expression has been shown to alter immunological signaling funct...

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Detalles Bibliográficos
Autores principales: Herek, Tyler A., Robinson, Jacob E., Heavican, Tayla B., Amador, Catalina, Iqbal, Javeed, Cutucache, Christine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043983/
https://www.ncbi.nlm.nih.gov/pubmed/30005686
http://dx.doi.org/10.1186/s13104-018-3583-3