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Key role of piRNAs in telomeric chromatin maintenance and telomere nuclear positioning in Drosophila germline

BACKGROUND: Telomeric small RNAs related to PIWI-interacting RNAs (piRNAs) have been described in various eukaryotes; however, their role in germline-specific telomere function remains poorly understood. Using a Drosophila model, we performed an in-depth study of the biogenesis of telomeric piRNAs a...

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Detalles Bibliográficos
Autores principales: Radion, Elizaveta, Morgunova, Valeriya, Ryazansky, Sergei, Akulenko, Natalia, Lavrov, Sergey, Abramov, Yuri, Komarov, Pavel A., Glukhov, Sergey I., Olovnikov, Ivan, Kalmykova, Alla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043984/
https://www.ncbi.nlm.nih.gov/pubmed/30001204
http://dx.doi.org/10.1186/s13072-018-0210-4