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Differentially methylated loci in NAFLD cirrhosis are associated with key signaling pathways

Altered DNA methylation events contribute to the pathogenesis and progression of metabolic disorders, including nonalcoholic fatty liver disease (NAFLD). Investigations of global DNA methylation patterns in liver biopsies representing severe NAFLD fibrosis have been limited. We used the HumanMethyla...

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Detalles Bibliográficos
Autores principales: Gerhard, Glenn S., Malenica, Ivana, Llaci, Lorida, Chu, Xin, Petrick, Anthony T., Still, Christopher D., DiStefano, Johanna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044005/
https://www.ncbi.nlm.nih.gov/pubmed/30005700
http://dx.doi.org/10.1186/s13148-018-0525-9