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Exosomal miR-9 inhibits angiogenesis by targeting MDK and regulating PDK/AKT pathway in nasopharyngeal carcinoma

BACKGROUND: Exosomes are small vesicles containing a wide range of functional proteins, mRNA and miRNA. Exosomal miRNAs from cancer cells play crucial roles in mediating cell-cell communication and tumor-microenvironment cross talk, specifically in enabling metastasis and promoting angiogenesis. We...

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Detalles Bibliográficos
Autores principales: Lu, Juan, Liu, Qi-Hui, Wang, Fan, Tan, Jia-Jie, Deng, Yue-Qin, Peng, Xiao-Hong, Liu, Xiong, Zhang, Bao, Xu, Xia, Li, Xiang-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044044/
https://www.ncbi.nlm.nih.gov/pubmed/30001734
http://dx.doi.org/10.1186/s13046-018-0814-3