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A robust gene regulatory network inference method base on Kalman filter and linear regression

The reconstruction of the topology of gene regulatory networks (GRNs) using high throughput genomic data such as microarray gene expression data is an important problem in systems biology. The main challenge in gene expression data is the high number of genes and low number of samples; also the data...

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Detalles Bibliográficos
Autores principales: Pirgazi, Jamshid, Khanteymoori, Ali Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044105/
https://www.ncbi.nlm.nih.gov/pubmed/30001352
http://dx.doi.org/10.1371/journal.pone.0200094