Intestinal Stem Cells to Advance Drug Development, Precision, and Regenerative Medicine: A Paradigm Shift in Translational Research

Recent advances in our understanding of the intestinal stem cell niche and the role of key signaling pathways on cell growth and maintenance have allowed the development of fully differentiated epithelial cells in 3D organoids. Stem cell-derived organoids carry significant levels of proteins that ar...

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Detalles Bibliográficos
Autores principales: Mochel, Jonathan P., Jergens, Albert E., Kingsbury, Dawn, Kim, Hyun Jung, Martín, Martín G., Allenspach, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044282/
https://www.ncbi.nlm.nih.gov/pubmed/29234895
http://dx.doi.org/10.1208/s12248-017-0178-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044282/
https://www.ncbi.nlm.nih.gov/pubmed/29234895
http://dx.doi.org/10.1208/s12248-017-0178-1

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