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Intestinal Stem Cells to Advance Drug Development, Precision, and Regenerative Medicine: A Paradigm Shift in Translational Research
Recent advances in our understanding of the intestinal stem cell niche and the role of key signaling pathways on cell growth and maintenance have allowed the development of fully differentiated epithelial cells in 3D organoids. Stem cell-derived organoids carry significant levels of proteins that ar...
Autores principales: | Mochel, Jonathan P., Jergens, Albert E., Kingsbury, Dawn, Kim, Hyun Jung, Martín, Martín G., Allenspach, Karin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044282/ https://www.ncbi.nlm.nih.gov/pubmed/29234895 http://dx.doi.org/10.1208/s12248-017-0178-1 |
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