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SIRT4 acts as a tumor suppressor in gastric cancer by inhibiting cell proliferation, migration, and invasion

BACKGROUND: Previous study has proven that SIRT4 is downregulated in gastric cancer (GC), but the role of SIRT4 has not been clearly understood. The aim of our work was to explore in detail the function and mechanism of SIRT4 in GC. METHODS: A total of 86 pairs of GC tumor tissues and adjacent norma...

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Detalles Bibliográficos
Autores principales: Sun, Hongjie, Huang, Dongli, Liu, Guozheng, Jian, Fengguo, Zhu, Jianfang, Zhang, Lixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044351/
https://www.ncbi.nlm.nih.gov/pubmed/30022839
http://dx.doi.org/10.2147/OTT.S156143