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InDePTH: detection of hub genes for developing gene expression networks under anticancer drug treatment

It has been difficult to elucidate the structure of gene regulatory networks under anticancer drug treatment. Here, we developed an algorithm to highlight the hub genes that play a major role in creating the upstream and downstream relationships within a given set of differentially expressed genes....

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Detalles Bibliográficos
Autores principales: Koido, Masaru, Tani, Yuri, Tsukahara, Satomi, Okamoto, Yuka, Tomida, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044382/
https://www.ncbi.nlm.nih.gov/pubmed/30018738
http://dx.doi.org/10.18632/oncotarget.25624