Cargando…

InDePTH: detection of hub genes for developing gene expression networks under anticancer drug treatment

It has been difficult to elucidate the structure of gene regulatory networks under anticancer drug treatment. Here, we developed an algorithm to highlight the hub genes that play a major role in creating the upstream and downstream relationships within a given set of differentially expressed genes....

Descripción completa

Detalles Bibliográficos
Autores principales:	Koido, Masaru, Tani, Yuri, Tsukahara, Satomi, Okamoto, Yuka, Tomida, Akihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044382/ https://www.ncbi.nlm.nih.gov/pubmed/30018738 http://dx.doi.org/10.18632/oncotarget.25624

Ejemplares similares

Disrupting ATF4 Expression Mechanisms Provides an Effective Strategy for BRAF-Targeted Melanoma Therapy
por: Nagasawa, Ikuko, et al.
Publicado: (2020)

Spautin-1 inhibits mitochondrial complex I and leads to suppression of the unfolded protein response and cell survival during glucose starvation
por: Kunimasa, Kazuhiro, et al.
Publicado: (2022)

Mitochondrial deficiency impairs hypoxic induction of HIF-1 transcriptional activity and retards tumor growth
por: Koido, Masaru, et al.
Publicado: (2017)

Foreword: INDEPTH WHO-SAGE study
por: Sankoh, Osman
Publicado: (2010)

The INDEPTH Network: filling vital gaps in global epidemiology
por: Sankoh, Osman, et al.
Publicado: (2012)

Monitoring the millennium development goals: the potential role of the INDEPTH Network
por: Bangha, Martin, et al.
Publicado: (2010)

INDEPTH @ 10: celebrate the past and illuminate the future
por: Evans, Tim, et al.
Publicado: (2008)

Optimization of PTH/PTHrP Hybrid Peptides to Derive a Long‐Acting PTH Analog (LA‐PTH)
por: Noda, Hiroshi, et al.
Publicado: (2020)

Foreword: The INDEPTH WHO-SAGE collaboration – coming of age
por: Boerma, Ties
Publicado: (2010)

Blood pressure in adult rural INDEPTH population in Asia
por: Van Minh, Hoang, et al.
Publicado: (2009)

Comprehensive transcriptomic analysis of molecularly targeted drugs in cancer for target pathway evaluation
por: Mashima, Tetsuo, et al.
Publicado: (2015)

Social factors and overweight: evidence from nine Asian INDEPTH Network sites
por: Razzaque, Abdur, et al.
Publicado: (2009)

The INDEPTH (Impact of Nuclear Domains on Gene Expression and Plant Traits) Academy: a community resource for plant science
por: Tatout, Christophe, et al.
Publicado: (2022)

The INDEPTH standard population for low- and middle-income countries, 2013
por: Sankoh, Osman, et al.
Publicado: (2014)

PTH Gene Polymorphism and Breast Cancer Risk in Kazakhstan
por: Sikhayeva, Nurgul, et al.
Publicado: (2014)

ComHub: Community predictions of hubs in gene regulatory networks
por: Åkesson, Julia, et al.
Publicado: (2021)

TBL2 Is a Novel PERK-Binding Protein that Modulates Stress-Signaling and Cell Survival during Endoplasmic Reticulum Stress
por: Tsukumo, Yoshinori, et al.
Publicado: (2014)

Foreword: Clustering of mortality at INDEPTH member Health and Demographic Surveillance Systems
por: Sankoh, Osman
Publicado: (2010)

“Every Newborn-INDEPTH” (EN-INDEPTH) study protocol for a randomised comparison of household survey modules for measuring stillbirths and neonatal deaths in five Health and Demographic Surveillance sites
por: Baschieri, Angela, et al.
Publicado: (2019)

Interactome of PTH-Regulated miRNAs and Their Predicted Target Genes for Investigating the Epigenetic Effects of PTH (1–34) in Bone Metabolism
por: Vrščaj, Lucija Ana, et al.
Publicado: (2022)

Fruit and vegetable consumption in rural adults population in INDEPTH HDSS sites in Asia
por: Kanungsukkasem, Uraiwan, et al.
Publicado: (2009)

Birthweight data completeness and quality in population-based surveys: EN-INDEPTH study
por: Biks, Gashaw Andargie, et al.
Publicado: (2021)

Stillbirth outcome capture and classification in population-based surveys: EN-INDEPTH study
por: Blencowe, Hannah, et al.
Publicado: (2021)

An Arabidopsis PTH2 Gene Is Responsible for Gravity Resistance Supporting Plant Growth under Different Gravity Conditions
por: Hattori, Takayuki, et al.
Publicado: (2022)

Rare PTH Gene Mutations Causing Parathyroid Disorders: A Review
por: Lee, Joon-Hyop, et al.
Publicado: (2020)

Social autopsy: INDEPTH Network experiences of utility, process, practices, and challenges in investigating causes and contributors to mortality
por: Källander, Karin, et al.
Publicado: (2011)

Effect of PTH and corticotomy on implant movement under mechanical force
por: Kim, Jiyeon, et al.
Publicado: (2020)

Mitochondrial Redox Hubs as Promising Targets for Anticancer Therapy
por: Ippolito, Luigi, et al.
Publicado: (2020)

Termination of pregnancy data completeness and feasibility in population-based surveys: EN-INDEPTH study
por: Enuameh, Yeetey Akpe Kwesi, et al.
Publicado: (2021)

Identification of hub genes and construction of transcriptional regulatory network for the progression of colon adenocarcinoma hub genes and TF regulatory network of colon adenocarcinoma
por: Wei, Shuxun, et al.
Publicado: (2019)

Identification of underlying mechanisms and hub gene-miRNA networks of the genomic subgroups in preeclampsia development
por: Zhang, Min, et al.
Publicado: (2022)

Evidence of Highly Regulated Genes (in-Hubs) in Gene Networks of Saccharomyces Cerevisiae
por: Lundström, Jesper, et al.
Publicado: (2008)

Enhanced construction of gene regulatory networks using hub gene information
por: Yu, Donghyeon, et al.
Publicado: (2017)

Network Analyses of Differentially Expressed Genes in Osteoarthritis to Identify Hub Genes
por: Li, Zhaoyan, et al.
Publicado: (2019)

Weighted gene co-expression network analysis identified underlying hub genes and mechanisms in the occurrence and development of viral myocarditis
por: Ma, Zetao, et al.
Publicado: (2020)

Gene structure, transcripts and calciotropic effects of the PTH family of peptides in Xenopus and chicken
por: Pinheiro, Pedro LC, et al.
Publicado: (2010)

Inverse correlation of intact PTH, oxidized PTH as well as non-oxidized PTH with 25-hydroxyvitamin D3 in kidney transplant recipients
por: Zuo, Jiao, et al.
Publicado: (2023)

Guest Editorial: Analyses of mortality clustering at member HDSSs within the INDEPTH Network – an important public health issue
por: Becher, Heiko
Publicado: (2010)

Text Mining and Hub Gene Network Analysis of Endometriosis
por: Wang, Yinuo, et al.
Publicado: (2021)

An Excess of CYP24A1, Lack of CaSR, and a Novel lncRNA Near the PTH Gene Characterize an Ectopic PTH-Producing Tumor
por: Uchida, Kosuke, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_5jn1ibmhdd1d7hu9n6fckhik84