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Regulation of the interferon-gamma (IFN-γ) pathway by p63 and Δ133p53 isoform in different breast cancer subtypes

The TP53 family consists of three sets of transcription factor genes, TP53, TP63 and TP73, each of which expresses multiple RNA variants and protein isoforms. Of these, TP53 is mutated in 25-30% of breast cancers. How TP53 mutations affect the interaction of TP53 family members and their isoforms in...

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Detalles Bibliográficos
Autores principales: Mehta, Sunali Y., Morten, Brianna C., Antony, Jisha, Henderson, Luke, Lasham, Annette, Campbell, Hamish, Cunliffe, Heather, Horsfield, Julia A., Reddel, Roger R., Avery-Kiejda, Kelly A., Print, Cristin G., Braithwaite, Antony W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044385/
https://www.ncbi.nlm.nih.gov/pubmed/30018742
http://dx.doi.org/10.18632/oncotarget.25635